Publications - Papers

  • AG Baumeister
    Nyamsuren, O.1, Faggionato, D.1, Loch, W., Schulze, E., Baumeister, R. (2007) A mutation in CHN-1/CHIP suppresses muscle degeneration in Caenorhabditis elegans. Dev. Biol. 312, 193-202. 1both authors contributed equally http://www.ncbi.nlm.nih.gov/

    Tullet, J.M., Hertweck, M., An, J.H., Baker, J., Hwang, J.Y., Liu, S., Oliveira, R.P., Baumeister, R., Blackwell, T.K. (2008). Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 132,1025-38

  • AG Borner
    Jo, Juandy; Bengsch, Bertram; Seigel, Bianca; Rau, Sibylle J.; Schmidt, Julia; Bisse, Emmanuel; Aichele, Peter; Aichele, Ulrike; Joeckel, Lars; Royer, Cathy; Ferreira, Karine S·; Borner, Christoph; Baumert, Thomas F.; Blum, Hubert E.; Lohmann, Volker; Fischer, Richard; Thimme, Robert (2012): Low perforin expression of early differentiated HCV-specific CD8+ T cells limits their hepatotoxic potential. In: Journal of hepatology, Mar 14 [Epub ahead of print].

    Ferreira, Karine S·; Kreutz, Clemens; Macnelly, Sabine; Neubert, Karin; Haber, Angelika; Bogyo, Matthew; Timmer, Jens; Borner, Christoph (2012): Caspase-3 feeds back on caspase-8, Bid and XIAP in type I Fas signaling in primary mouse hepatocytes. In: Apoptosis : an international journal on programmed cell death, Jan 13 [Epub ahead of print].

    Schmich, Kathrin; Schlatter, Rebekka; Corazza, Nadia; S· Ferreira, Karine; Ederer, Michael; Brunner, Thomas; Borner, Christoph; Merfort, Irmgard (2011): Tumor necrosis factor ? sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner. In: Hepatology 53 (1), S. 282?292.

    Philippi, Nicole; Walter, Dorothee; Schlatter, Rebekka; Ferreira, Karine; Ederer, Michael; Sawodny, Oliver; Timmer, Jens; Borner, Christoph; Dandekar, Thomas (2009): Modeling system states in livercells: survival, apoptosis and their modifications in response to viral infection. In: BMC Syst Biol 3, S. 97.

    Manoharan, A., Kiefer T., Leist, S., Schrader, K., Urban, C., Walter, D., Maurer, U. and Borner, C. (2006) Identification of a ‘genuine’ mammalian homolog of nematodal CED-4: is the hunt over or do we need better guns? Cell Death and Differentiation; 13 1310-1317

  • AG Brand-Saberi
    Rehimi, R., Khalida, N., Yusuf, F., Dai, F., Morosan-Puopolo, G., and Brand-Saberi, B. (2008). Stromal-derived factor-1 (SDF-1) expression during early chick development. Int J Dev Biol 52, 87-92.

    Zhang, X., Dai, F., Weise, C., Yusuf, F., Bonafede, A., Morosan-Puopolo, G., Rehimi, R., Wang, J., Brand-Saberi, B. (2006) Expression of the avian Nucleolar complex associated protein2 (NOC2) - homologue in embryonic development. Anat. Embryol. 211,649-658

  • AG Diefenbach
    Sanos, S.L., Bui, V.L., Mortha, A., Oberle, K., Ivanov, I.,. Heners, C. and Diefenbach, A. (2008). ROR?t and commensal microflora are required for the differentiation of mucosal interleukin 22-producing Nkp46+ cells. Nature Immunology. 10:83-91.

  • AG Driever
    Tay, T.L., Ronneberger, O., Ryu, S., Nitschke, R., Driever, W. (2011) Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Nat Commun, 2:171

    Mahler, J., Filippi, A., Driever, W. (2010) DeltaA/DeltaD regulate multiple and temporally distinct phases of notch signaling during dopaminergic neurogenesis in zebrafish. J Neurosci. 30(49):16621-35.

    Filippi, A., Mahler, J., Schweitzer, J., Driever, W. (2010) Expression of the paralogous tyrosine hydroxylase encoding genes th1 and th2 reveals the full complement of dopaminergic and noradrenergic neurons in zebrafish larval and juvenile brain. J Comp Neurol. 518(4):423-38

    Mahler, J., Driever, W., (2007) Expression of the zebrafish intermediate neurofilament Nestin in the developing nervous system and in neural proliferation zones at postembryonic stages. BMC Developmental Biology, 7:89 doi:10.1186/1471-213X-7-89

    Ryu S., Mahler J., Acampora D., Holzschuh J., Erhardt S., Omodei D., Simeone A., and Driever W. (2007) Orthopedia Homedomain Protein is Essential for Diencephalic Dopaminergic Neuron Development, Current Biology 17,1-8, 2007, doi 10.1016/j.cub.2007.04.003

    Ryu S., Holzschuh J., Mahler J., and Driever W. (2006) Genetic analysis of dopaminergic system development in zebrafish, J Neural Transm Suppl 2006:61-6

  • AG Hammerschmidt
    Laue, K., Jaenicke, M., Plaster, N., Sonntag, C., Hammerschmidt, M. (2008). Restriction of retinoic acid activity by Cyp26b1 is required for proper timing and patterning of osteogenesis during zebrafish development. Development, Nov;135(22):3775-87.

    Jänicke, M., Carney, T.J. and Hammerschmidt, M. (2007). Foxi3 transcription factors and Notch signaling control the formation of skin ionocytes from epidermal precursors of the zebrafish embryo. Dev. Biol. 307, 258-271.

  • AG Omran
    Loges, N., Olbrich, H., Fenske, L, Mussaffi, H., Horvath, J., Fliegauf, M., Kuhl, H., Baktai, G., Peterffy, E., Chodhari, R., Chung, E.M.K., Rutman, A., O’Callaghan, C., Blau, H., Tiszlavicz, L., Voelkel, K., Witt, M., Zietkiewicz, E., Neesen, J., Reinardt, R., Mitchison, H.M., Omran, H. (2008). DNAI2 Mutations Cause Primary Ciliary Dyskinesia with Defects in the Outer Dynein Arm. Am. J. Hum. Gen., doi: 10.1016/j.ajhg.2008, 10.001

    Omran, H., Kobayashi, D., Olbrich, H., Tsukahara, T., Loges, N.T., Hagiwara, H., Zhang, Q., Leblond, G., O’Toole, E., Hara, C., Mizuno, H., Kawano, H., Fliegauf, M., Yagi, T., Koshida, S., Miyawaki, A., Zentgraf, H.W., Seithe, H., Reinhardt, R., Watanabe, Y., Kamiya, R., Mitchell, D.R., Takeda, H (2008). Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins. Nature 456:611-6

    Schwabe, G.C., Hoffmann, K., Loges, N.T., Birker, D., Rossier, C., de Santi, M.M., Olbrich, H., Fliegauf, M., Failly, M., Liebers, U., Collura, M., Gaedicke, G., Mundlos, S., Wahn, U., Blouin, J.L., Niggemann, B., Omran, H., Antonarakis, S.E., Bartoloni, L. (2008). Primary ciliary dyskinesia associated with normal axoneme ultrastructure is caused by DNAH11 mutations. Hum. Mutat. 29, 289-298.

    Janzarik, W.G., Kratz, C.P., Loges, N.T., Olbrich, H., Klein, C., Schäfer, T., Scheurlen, W., Roggendorf, W., Weiller, C., Niemeyer, C., Korinthenberg, R., Pfister, S., Omran, H. (2007). Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma., Neuropediatrics. 38, 61-63.

    Hornef, N., Olbrich, H., Horvath, J., Zariwala, M.A., Fliegauf, M., Loges, N.T., Wildhaber, J., Noone, P.G., Kennedy, M., Antonarakis, S.E., Blouin, J.L., Bartoloni, L., Nüsslein, T., Ahrens, P., Griese, M., Kuhl, H., Sudbrak, R., Knowles, M.R., Reinhardt, R., Omran, H. (2006). DNAH5 mutations are a common cause of primary ciliary dyskinesia with outer dynein arm defects. Am. J. Respir. Crit. Care Med. 15; 120-126.

    Olbrich, H., Horváth, J., Fekete, A., Loges, N.T., Storm van's Gravesande, K., Blum, A., Hörmann, K., Omran, H. (2006). Axonemal localization of the dynein component DNAH5 is not altered in secondary ciliary dyskinesia. Pediatr. Res. 59, 418-422.

    Sass, J.O., Mohr, V., Olbrich, H., Engelke, U., Horvath, J., Fliegauf, M., Loges, N.T., Schweitzer-Krantz, S., Moebus, R., Weiler, P., Kispert, A., Superti-Furga, A., Wevers, R.A., Omran, H. (2006). Mutations in ACY1, the gene encoding aminoacylase 1, cause a novel inborn error of metabolism. Am. J. Hum. Genet. 78, 401-409.

    Zariwala, M.A., Leigh, M.W., Ceppa, F., Kennedy, M.P., Noone, P.G., Carson, J.L., Hazucha, M.J., Lori, A., Horvath, J., Olbrich, H., Loges, N.T., Bridoux, A.M., Pennarun, G., Duriez, B., Escudier, E., Mitchison, H.M., Chodhari, R., Chung, E.M., Morgan, L.C., de Iongh, R.U., Rutland, J., Pradal, U., Omran, H., Amselem, S., Knowles, M.R. (2006). Mutations of DNAI1 in primary ciliary dyskinesia: evidence of founder effect in a common mutation. Am. J. Respir. Crit. Care Med. 174, 858-866.

  • AG Pyrowolakis
    Fuchs A., Cheung L.C., Charbonnier E., Shvartsman S.Y., Pyrowolakis G. (2012): Transcriptional interpretation of the EGF receptor signaling gradient. In: PNAS vol. 109 (5) 1572-1577

  • AG Scaal
    Wiegreffe, C., Christ, B., Huang, R., Scaal, M. (2009).Remodeling of aortic smooth muscle during avian embryonic development. Dev. Dyn. 238, 624-31.

    Wiegreffe, C., Christ, B., Huang, R., and Scaal, M. (2007). Sclerotomal origin of smooth muscle cells in the wall of the avian dorsal aorta. Dev Dyn 236, 2578-2585

    Scaal, M., and Wiegreffe, C. (2006). Somite compartments in anamniotes. Anatomy and embryology 211 Suppl 1, 9-19.

  • AG Scherer
    Barrionuevo, F., Georg, I., Scherthan, H., Lecureuil, C., Guillou, F., Wegner, M., and Scherer, G.:Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev. Biol. (in press).

  • AG Walz
    Schäfer, T., Pütz, M., Lienkamp, S., Ganner, A., Bergbreiter, A. Ramachandran, H., Gieloff, V., Gerner, M., Mattonet, C., Czarnecki, P.G., Sayer, J.A., Otto, E.A., Hildebrandt, F., Kramer-Zucker, A., Walz, G. (2008). Genetic and physical interaction between the NPHP5 and NPHP6 gene products. Hum Mol Genet

    Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. Skouloudaki K, Puetz M, Simons M, Courbard JR, Boehlke C, Hartleben B, Engel C, Moeller MJ, Englert C, Bollig F, Schäfer T, Ramachandran H, Mlodzik M, Huber TB, Kuehn EW, Kim E, Kramer-Zucker A, Walz G. Proc Natl Acad Sci U S A. 2009 May 13.